Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs through XBP-1-mediated activation of Akt
- Creator: Jiang, Chen Chen , Yang, Fan , Thorne, Rick F. , Zhu, Bi Ke , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2009
Progression in melanoma is associated with decreased expression of death receptors for tumor necrosis factor–related apoptosis-inducing ligand
- Creator: Zhuang, Liqing , Lee, C. Soon , Scolyer, Richard A. , McCarthy, Stanley W. , Zhang, Xu Dong , Thompson, John F. , Screaton, Gavin , Hersey, Peter
- Resource Type: journal article
- Date: 2006
Inhibition of apoptosis facilitates necrosis induced by cisplatin in gastric cancer cells
- Creator: Zhang, Lin Jie , Hao, Yuan Zhang , Hu, Chun Song , Ye, Yan , Xie, Qi Peng , Thorne, Rick F. , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2008
Phase I/II study of immunotherapy with T-cell peptide epitopes in patients with stage IV melanoma
- Creator: Hersey, Peter , Nguyen, T. , Farrelly, M. , Menzies, S.W. , Hirst, D. , Johnson, H. , Coventry, B. , Collins, S.
- Resource Type: journal article
- Date: 2005
Melanoma cell sensitivity to docetaxal-induced apoptosis is determined by class III β-tubulin levels
- Creator: Mhaidat, Nizar M. , Thorne, Rick F. , De Bock, Charles Edo , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2008
Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells
- Creator: Jiang, Chen Chen , Mao, Zhi Gang , Avery-Kiejda, Kelly A. , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2009
Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737
- Creator: Lucas, Keryn M. , Mohana-Kumaran, Nethia , Lau, Diana , Zhang, Xu Dong , Hersey, Peter , Huang, David C. , Weninger, Wolfgang , Haass, Nikolas K. , Allen, John D.
- Resource Type: journal article
- Date: 2012
MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma
- Creator: Jin, Lei , Hu, Wang Lai , Hersey, Peter , Zhang, Xu Dong , Wu, Mian , Jiang, Chen Chen , Wang, Jia Xu , Han, Chuan Chun , Chu, Ping , Zhang, Lin Jie , Thorne, Rick F. , Wilmott, James , Scolyer, Richard A.
- Resource Type: journal article
- Date: 2011
Expression of glucose-regulated stress protein GRP78 is related to progression of melanoma
- Creator: Zhuang, Liquing , Scolyer, Richard A. , Lee, C. Soon , McCarthy, Stanley W. , Cooper, Wendy A. , Zhang, Xu Dong , Thompson, John F. , Hersey, Peter
- Resource Type: journal article
- Date: 2009
Regulators of global genome repair do not respond to DNA damaging therapy but correlate with survival in melanoma
- Creator: Bowden, Nikola A. , Ashton, Katie A. , Scott, Rodney J. , Vilain, Ricardo E. , Avery-Kiejda, Kelly A. , Davey, Ryan J. , Murray, Heather C. , Budden, Timothy , Braye, Stephen G. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2013
Evaluation of immune-related response criteria and RECIST v1.1 in patients with advanced melanoma treated with pembrolizumab
- Creator: Hodi, F. Stephen , Hwu, Wen-Jen , Joshua, Anthony M. , Hersey, Peter , Dronca, Roxana , Joseph, Richard , Hille, Darcy , Xue, Dahai , Li, Xiaoyun Nicole , Kang, S. Peter , Ebbinghaus, Scot , Perrone, Andrea , Kefford, Richard , Wolchok, Jedd D. , Weber, Jeffrey S. , Daud, Adil , Hamid, Omid , Patnaik, Amita , Ribas, Antoni , Robert, Caroline , Gangadhar, Tara C.
- Resource Type: journal article
- Date: 2016
Melanoma early detection and awareness: how countries developing melanoma awareness programs could benefit from melanoma-proficient countries
- Creator: Wainstein, Alberto , Algarra, Salvador Martin , Whitaker, Dagmar , Quirt, Ian , Hauschild, Axel , Rutkowski, Piotr , Bastholt, Lars , Cinat, Gabriela , Demidov, Lev , Grob, Jean Jacques , Guo, Jun , Hersey, Peter , Espinosa, Enrique , Schachter, Jacob
- Resource Type: journal article
- Date: 2015
MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720
- Creator: Jiang, Chen Chen , Lai, Fritz , Thorne, Rick F. , Yang, Fan , Liu, Hao , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2011
Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma
- Creator: Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2008
Somatic copy number amplification and hyperactivating somatic mutations of EZH2 correlate with DNA methylation and drive epigenetic silencing of genes involved in tumor suppression and immune responses in melanoma
- Creator: Tiffen, Jessamy , Wilson, Stephen , Gallagher, Stuart J. , Hersey, Peter , Filipp, Fabian V.
- Resource Type: journal article
- Date: 2016
The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance
- Creator: Wroblewski, David , Mijatov, Branka , Mohana-Kumaran, Nethia , Lai, Fritz , Gallagher, Stuart J. , Haass, Nikolas K. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2013
Phase II trial of tremelimumab (CP-675,206) in patients with advanced refractory or relapsed melanoma
- Creator: Kirkwood, John M. , Lorigan, Paul , Hersey, Peter , Hauschild, Axel , Robert, Caroline , McDermott, David , Marshall, Margaret A. , Gomez-Navarro, Jesus , Liang, Jane Q. , Bulanhagui, Cecile A.
- Resource Type: journal article
- Date: 2010
The melanoma-associated antigen MAGE-D2 suppresses TRAIL receptor 2 and protects against TRAIL-induced apoptosis in human melanoma cells
- Creator: Tseng, Hsin-Yi , Chen, Li Hua , Ye, Yan , Tay, Kwang Hong , Jiang, Chen Chen , Guo, Su Tang , Jin, Lei , Hersey, Peter , Zhang, Xu Dong
- Resource Type: journal article
- Date: 2012
Inhibition of endoplasmic reticulum stress-induced apoptosis of melanoma cells by the ARC protein
- Creator: Chen, Li Hua , Jiang, Chen Chen , Watts, Ralph , Thorne, Rick F. , Kiejda, Kelly A. , Zhang, Xu Dong , Hersey, Peter
- Resource Type: journal article
- Date: 2008
Results of a phase III, randomized, placebo-controlled study of sorafenib in combination with Carboplatin and Paclitaxel as second-line treatment in patients with unresectable stage III or stage IV melanoma
- Creator: Hauschild, Axel , Agarwala, Sanjiv S , Peschel, Christian , Schadendorf, Dirk , Garbe, Claus , O'Day, Steven , Daud, Adil , White, J. Michael , Xia, Chenghua , Patel, Kiran , Kirkwood, John M. , Keilholz, Ulrich , Trefzer, Uwe , Hogg, David , Robert, Caroline , Hersey, Peter , Eggermont, Alexander , Grabbe, Stephan , Gonzalez, Rene , Gille, Jens
- Resource Type: journal article
- Date: 2009